Mauro Tambasco, Ph.D.
Pronouns: Mauro
Associate Professor of Physics
College of Sciences
Department of Physics
San Diego
- mtambasco@sdsu.edu
- Phone
- 619-594-6161
- Office Hours
-
TBA
- Location
- P 139
5500 Campanile Dr
San Diego, CA 92182 - Mail Code
- 1233
- Fax
- 619-594-5484
- Links
- Website
- Accounts
Areas of Expertise
Radiation Oncology Physics, Radiation Biology, 3D Tumor Bioprinting, Evolutionary Dynamics of Tumor Resistance to Treatment
Bio
The main focus areas of my research include:
Using 3D bioprinting technology to develop tissue mimetic tumor models that can be used to study and optimize the effects of spatially fractionated radiotherapy (SFRT) approaches such as GRID, LATTICE, and PATHY.
Applying 3D bioprinted co-culture tumor models to investigate and optimize the use of SFRT techniques for immune priming. This is done using SFRT combined with immune checkpoint inhibition, radiosensitizers, and a pulsed treatment approach to overcome the treatment-induced evolutionary resistance of tumor cells.
Developing a transportable 3D cell culture platform for assessing 2D distributions of relative biological effectiveness of proton radiotherapy beams and emerging radiotherapy technologies such as FLASH.